This was a slightly frustrating episode. Although plenty went on in All In The Family, it felt as though not much actually happened.
Chuck aka God revealed his plan to negotiate with Amara, with the idea of letting her cage him as he did her, if she leaves the Universe alone.
However, the Winchesters know - because of Dean's conversations with Amara - that all she wants to do is obliterate everything. Instead, they hatch a plan to rescue Lucifer, from Amara's clutches, so he can team up with God and take Amara down.
Conveniently she's torturing Lucifer in an abandoned warehouse rather than, I don't know, on another planet, in another dimension, or somewhere outside of the United States.
Along the way the Winchesters meet a new Prophet, an atheist teacher called Donatello Redfield (Keith Szarabajka), a lone survivor of one of Amara's deadly (and seemingly random and quite possibly pointless) killer fog attacks.
Amara has been appearing to Dean in visions, playing up her 'attraction' to him and their connection, and so it's his job to distract her while Sam, Donatello and Metatron rescue Lucifer.
I think a growing problem I'm having with this season - which started off so fantastically and has had many, many stand-out episodes - is that the writers have thrown two omnipotent, omniscient characters into the mix (ie. God and his sister), but have now realised they've written themselves into a corner by raising the stakes (and power levels) to cosmic levels.
As Dean says at one point, this is "above his pay grade", and I just can't see how the season story arc can be resolved without an almighty (pardon the pun) cop-out, some serious back-pedalling, or reducing these major players to the Winchesters' level.
Clearly, the connection between Dean - the former wearer of The Mark, which imprisoned her - and Amara will be the key to all this. I just hope it's handled with some novelty and imagination.