While Sam remains in Nebraska, fighting off infected zombies and trying to find a cure, Dean delivers Jenna Nickerson (Laci J Mailey), and baby Amara, to her Catholic grandmother (Christine Willes) for safety.
Unfortunately, no sooner does Dean leave than the baby starts exhibiting supernatural powers, prompting Jenna to call Dean back. But before he can return, her grandmother has contacted her local church and they've called in an exorcist... who just happens to be 'Father' Crowley!
Elsewhere, Castiel is being tortured by his fellow angels, who are looking for Metatron. Hannah (Lee Majdoub), now in male form, turns up to save him, but Castiel quickly realises it's a trick.
Struck by Hellraiser-esque visions, Sam gets a visit from a Reaper, Billie (Lisa Berry), who informs him that the Winchesters' previous revolving door policy to death has now been revoked and the next time either of the brothers dies, it will be forever.
She does, however, either willingly or accidentally, give Sam a clue towards the cure for the black vein infection.
Dean and Crowley discover that Amara not only is The Darkness in human form, but that she also eats souls.
Continuing the grim ambience of Out of the Darkness, Into the Fire, Form And Void signalled that this new status quo was here to stay (for a while, at least), and that maybe - just maybe - the Winchesters weren't guaranteed an automatic win.
Form And Void also reminded us, in both words and deeds, that Crowley, while witty and charming, is not the Winchesters' "sidekick" but is, in fact, the King Of Hell.